Re: [GRG] Stem Cell Fate Determined by Surface SmoothnessHow timely! “Stem cell niches” are finally receiving due attention.
Ramos, F.J., and M. Kaeberlein, A healthy diet for stem cells. Nature 486:477-8; 2012.
Yilmaz, O.H., et al., mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. Nature 486:490-5; 2012.
On 3/31/13 3:53 PM, “L. Stephen Coles, M.D., Ph.D.” wrote:
To Members and Friends of the Los Angeles Gerontology Research Group:
Stem cell fate determined by its grip to a surface. — Steve Coles
Stem Cell Fate Depends on ‘Grip’
March 29, 2013; (Bioscience and Technology) — A team of researchers has generated new insight on how a stem cell’s environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can “grip” the material they are growing in.
L. Stephen Coles, M.D., Ph.D., Co-Founder
Los Angeles Gerontology Research GroupURL: http://www.grg.org E-mail: firstname.lastname@example.orgE-mail: email@example.com