To Members and Friends of the Los Angeles Gerontology
Research Group: Maria’s
Editorial in Russian/English edited into better English below. Her heart
is in the right place, but she needs to do a better job in bleaching her
hair if she insists that everyone needs to know what she looks like with
her nail polish up front :-)… — Steve Coles
From: “Maria Konovalenko”
Subject: [New post] Nine Obvious Steps to Immortality
Maria Konovalenko posted:
1. Use personalized medicine services. Get a lot of data
about the state of your own body. First of all, it?s various ?omics?:
genomics, transcriptomics, epigenomics, proteomics, and metabolomics. You
can purchase a US$100.00 23andme test or a half-million dollar
“New post by Maria
9 Obvious Steps to Immortality
Wednesday, July 30, 2014 at 19:14;
1. Use personalized medicine
services. Get a lot of data about the state of your own body.
First of all, it?s various ?omics?: genomics,
transcriptomics, epigenomics, proteomics, and metabolomics. You can do a
US$100 23andme test or a half-million dollar analysis the way Dr.
Michael Snyder, Chair of Genetics at Stanford University, did. He
measured 40,000 of his own biological lab parameters over quite a long
2. Participate in clinical trials of geroprotector drug candidates.
Several pharmacologic drugs are now known to extend the lifespans of
model animals. The time for human clinical trials has come. Of course,
another option for those who don’t want to participate themselves is to
support such studies financially and/or organizationally.
3. Personalized science — treat your health as a scientific
objective. You should identify the existing and potential pathologies in
your body and figure out a way to treat and prevent them.
Right now the elements of personalized science are
used in treating cancer: People do cancer cell-genome sequencing and
compare it to the genome of a healthy cell to identify what went wrong
and led to the diseases. They also do experiments with the tumor by
transplanting it into mice to identify the drugs that may work for the
particular patient. This basically means that experiments are done to
tackle the problem of a given person. To stay healthy, it is a good idea
to start fighting those diseases that haven’t yet manifested and try to
4. Organize scientific research. Steve Jobs, Apple CEO, wasn’t treating
his cancer for the first several months after it was detected; he was
relying on yoga and meditation [and carrot juice]. What he could have
done was to build an Institute for Bioengineering Pancreas and Liver and
engage in scientific studies. There are a lot of great experiments that
need to be organized, for example, studying integrated longevity gene
therapy or else one could become an amateur scientist and build a home
lab and test geroprotector candidates in old mice.
5. Be friends with people with no harmful habits, who are on
calorie-restricted diets, physically active, and interested in science.
And be that way yourself.
6. Create crowd-funding campaigns in the area of longevity. Researchers
need a lot of money to do good science. Studies into the phenomenon of
life extension and basic mechanisms of aging have pathetic levels
funding. We need to advertise the work of scientists that will save
millions of lives with the help of crowd-funding platforms.
7. Increase your own competence. Knowledge quite literally extends
lifespan. The mechanism of this is not clear yet, but maybe it is due to
neurogenesis. New neurons are formed in our brains, but if we don’t use
them to form new knowledge, they die. Perhaps it is best to study
molecular biology, because this kind of knowledge can be applied to your
8. Sign a cryonics contract for neuropreservation and leave as much
information about yourself as possible.
9. Promote the value of human longevity. Public opinion defines
government policy. It is necessary to make the government realize the
main right of every citizen is the “right to live.” Aging
kills the vast majority of all humans. Various social institutions
have to appreciate this and start solving the problem.