[GRG] New Study of Longevity Predictors

Dear Colleagues,
We are pleased to alert you about our new published peer-reviewed study
of longevity predictors:

Predictors of Exceptional Longevity:
Effects of Early-Life Childhood Conditions, Mid-Life Environment and
Parental CharacteristicsGavrilov L.A., Gavrilova N.S.
In:

2014 Living to 100 Monograph  [published online 
–  August, 2014,
http://livingto100.
soa.org/].
The Society of Actuaries, 2014, 18 pages
Full text is available at:
http://ift.tt/1ufZXNG

Abstract:     Knowledge of strong predictors of mortality
and longevity is very important for actuarial science and practice.
Earlier studies found that parental characteristics as well as early-life
conditions and midlife environment play a significant role in survival to
advanced ages. However, little is known about the simultaneous effects of
these three factors on longevity. This ongoing study attempts to fill
this gap by comparing centenarians born in the United States in 1890–91
with peers born in the same years who died at age 65. The records for
centenarians and controls were taken from computerized family histories,
which were then linked to 1900 and 1930 U.S. censuses. As a result of
this linkage procedure, 765 records of confirmed centenarians and 783
records of controls were obtained.
     Analysis with multivariate logistic regression
found that parental longevity and some midlife characteristics proved to
be significant predictors of longevity while the role of childhood
conditions was less important. More centenarians were born in the second
half of the year compared to controls, suggesting early origins of
longevity. We found the existence of both general and gender-specific
predictors of human longevity. General predictors common for men and
women are paternal and maternal longevity. Gender-specific predictors of
male longevity are the farmer occupation at age 40, Northeastern region
of birth in the United States and birth in the second half of year. A
gender-specific predictor of female longevity is surprisingly the
availability of radio in the household according to the 1930 U.S.
census.
     Given the importance of familial longevity as an
independent predictor of survival to advanced ages, we conducted a
comparative study of biological and nonbiological relatives of
centenarians using a larger sample of 1,945 validated U.S. centenarians
born in 1880–95. We found that male gender of centenarian has significant
positive effect on survival of adult male relatives (brothers and
fathers) but not female blood relatives. Life span of centenarian
siblings-in-law is lower compared to life span of centenarian siblings
and does not depend on centenarian gender. Wives of male centenarians
(who share lifestyle and living conditions) have a significantly better
survival compared to wives of centenarians’ brothers. This finding
demonstrates an important role of shared familial environment and
lifestyle in human longevity.
     The results of this study suggest that familial
background, early-life conditions and midlife characteristics play an
important role in longevity. This study was supported by National
Institutes of Health (NIH) grant R01 AG028620.

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About Johnny Adams

My full-time commitment is to slow and ultimately reverse age related functional decline to increase healthy years of life. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Carl I. Bourhenne Medical Research Foundation (Aging Intervention Foundation), an IRS approved 501(c)(3) nonprofit. http://www.AgingIntervention.org Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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