Being somewhat incorrigible, this emails asks if anyone is aware of data and detailed discussions in that regard?
PS / certainly not new information to people here :
— why it is interesting: in mouse models rapamycin was repeatedly found to increase lifespan when taken at a later age. This is in contrast with calroci restriction for which most starts at a late age did not show significant mouse life extension
— why it is likely a question in the air: at usual doses the drug comes with strong side effects so there might not be many cases put together of somewhat healthy persons taking rapamycin at lower doses for a prolongd period of time. Perhaps: safety trials
that preceeded commercialization? uses after engraftments in cases when the rejection risk is not very problematic? post-cancer use?