Yes, that’s the paper I was thinking of.
I believe greater extensions have been reported,
at least when measured as a percent of the
lifespan of control mice.
On 06/07/14 19:03, Reason wrote:
> On 06/07/2014 05:19 PM, email@example.com wrote:
> >On 06/06/14 20:48, Reason wrote:
> >>Isn’t the biggest effect in mice achieved
> >>through GHRKO or similar, discovered quite early
> >>in this modern phase of investigation, and still
> >I checked my big spread sheet of life span
> >experiments for studies of GHRKO in mice.
> >It has mouse experiments with better results.
> >However, I find myself wondering precisely which
> >GHRKO study you’re thinking of.
> >If you happen to have the time, and are so
> >inclined, maybe you could provide a full citation
> >for the study you were thinking of.
> This is the paper I usually turn up for discussion of GHRKO and similar
> around the time of interest (2004), but it is a summary of the prior years
> of work and a collection of references.
> Offhand I’m not sure which of Andrzej Bartke’s papers reports on the study
> that gave rise to the mouse GHR-KO 11C that received for the inaugural
> Mprize award, age at death 1819 days. But it would be one of those preceding
> and informing the paper above, and is probably referenced in it.
> I would be marginally interested to hear of studies that you think have
> shown greater life extension than that in mice.