Re: [GRG] C60 Fullerenes for AntiAging?

Good morning Edouard,

The campaign is not finished yet, but yes, we will be starting a cancer study using c60. More specifically, we will be using NSG mice to assess human leukemia proliferation in vivo. Obviously leukemias behave differently than solid tumors might, but its a starting point to further study the effects of c60 on cancer.

Of note, we will also be conducting a lifespan study on middle-aged C57BL/6 mice for a different project. Group size will be 45 and we will be assessing about a dozen age-related biomarkers in addition to basics like CBC, appearance, and mass.

If you see any opportunities to collaborate please feel free to touch base. We’re very interested in making friends with anyone in the aging space.

Kelsey

Kelsey Moody, MBAChief Executive OfficerIchor Therapeutics, Inc.

217 Bryant AvenueSyracuse, NY 13204(518) 420-5004

http://ift.tt/YLJOGP

On Mon, Sep 15, 2014 at 5:22 AM, Edouard Debonneuil wrote:

 

Hello,

 

Following the initial report that c60-in-olive-oil extended the lifespan of rats (Baati et al, 2012, http://ift.tt/Xn6HyM) and the consecutive !mini! lifespantest on 3 mice at home,

 

— various persons have started to indicate on LongeCity that they take c60 but at this time long-term evidence is totally lacking and short term positive
health effects are questionable. The following experiments might give more clues:

 

— a c60 survival test in mice is starting in Iryna Pishel’s lab to reproduce the lifespan test of the initial report (with a bigger N but in mice instead of rats; we initially checked that c60 administered orally is absorbed in mice) // we thank the International Longevity Alliance, and SENS, Heales and Sceaux Longévité Santé for handling a 22k$ crowdfunding, and we thank LongeCity for a 0.5k$ grant. A communication should soon take place (currently we are instead busy preparing
experiments)

 

— I read that a test on the proliferation of human cancer cells grafted in mice is going to start in Kelsey Moody’s lab, with the help of LongeCity

 

Cheers

Edouard

De : L. Stephen Coles M.D. Ph.D.
À : Gerontology Research Group Cc : Ray Elliott Envoyé le : Lundi 15 septembre 2014 4h54Objet : Re: [GRG] C60 Fullerenes for AntiAging?

At 06:59 PM 9/14/2014, you wrote:
Dr. Coles,
    I have been reading about your organization. 
Have any of your members tried using C60 Buckyballs
(Fullerenes)?
Many thanks,
Ray Elliott

L. Stephen Coles, M.D., Ph.D., Cofounder
Los Angeles Gerontology Research GroupE-mail:

scoles@grg.orgE-mail:
scoles@ucla.edu

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About Johnny Adams

My full-time commitment is to slow and ultimately reverse age related functional decline to increase healthy years of life. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Carl I. Bourhenne Medical Research Foundation (Aging Intervention Foundation), an IRS approved 501(c)(3) nonprofit. http://www.AgingIntervention.org Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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