A few years ago we derived a signature of mammalian aging using
microarray data from multiple tissues:http://ift.tt/1GLmUj5
it’s been well used by others and if you are only interested in
specific tissues then you can look at the datasets that we used
most of it is on our Digital Aging Atlas, in fact, which also
includes aging gene expression profiles from more recent studies:http://ageing-map.org/
I hope this helps.
On 21/12/2014 01:00, Natalie Jones
collaborators just completed a study comparing changes in
gene expression, miRNA and methylation profiles during
aging, and we hope to publish it soon. The oldest patient in
the study was 96. They have really cool algorithms that can
make sense of gene expression data even when it is partially
degraded allowing them to work with post mortem data and
they would be willing to share authorship and maybe even
some IP. Does
anyone have gene expression / miRNA datasets from
centenarians/supercentenarians from any tissues?
you know if these data sets exist? Does anyone who has
access to these data sets?