For what it’s worth, evidently a homolog of GDF11
extended the lifespan of fruit flies.
I hope that helps,
On 01/01/15 19:26, steve hill wrote:
> Good Morning, I am wondering if anyone has been following the progress of this study which has used young blood to rejuvenate old mice? This was an update to the reports published earlier this year: Main points of the article in the link below are:
> – point A: A single blood protein called GDF11—can regenerate some organs in the body. (a previous experiment with Wagers et al) showed GDF11 reverses some age related cardiac hypertrophy)- point B: A related Phase 1 clinical trial is giving 18 Human patients with mild-to-moderate Alzheimer’s transfusions of young blood.- point C: No increased evidence of Cancer so far.
> No lifespan increase was reported according to the papers:
> Aged Mice Repeatedly Injected with Plasma from Young Mice: A Survival Study
> Amy Wagers according to another report would be looking at clinical trials within 3-5 years which is astoundingly slow. A small clinical trial is underway to treat AD patients to see if it helps, results should be in around a years time.
> GDF11 alone doesn’t seem to do much and even full plasma seemed to have little effect bar in the short term in some tissue and organs. I wonder if human trials will be similar?
> Regards Steve H