On 15-02-10 11:13 AM, Anthony Loera wrote:
Wouldn’t NAD be better than Nicotinamide Riboside
from chromadex, which is what this product contains?
Although the LEF product that I am taking contains nicotinamine
riboside (NR) as a registered trademarked product NIAGEN produced by
the Chromadex company, I doubt that the Elysium Health product will
contain NIAGEN. Nicotinamide is produced in the human body on the
path to making NAD and is not patentable as a chemical, as I
understand things (certainly as they should be!). Although a use
patent could be obtained for some disease or dysfunction defined by
the FDA, that is not what Elysium Health is promoting it for. There
are many possible sources of NR. The only reason I have waited for
NR to become available from some US supplement supplier is because
it takes a lot of time effort and capital to import a supply from
China or elsewhere, and no chemical supplier in the US or Canada
would sell me any as an individual, particularly not for personal
use. Several other such chemicals, I did not wait for, but this one
I decided to do so, partly because of the lack of clear research for
benefits greater than NAD or simply taking more niacin.
Note that I erred previously (skimmed too much) by not reading the
“Guarente says Elysiumâ€™s pill includes a precursor to NAD, called
nicotinamide riboside, which the body can transform into NAD and put
to use. In addition, the pill contains pterostilbene, an antioxidant
that Guarente says stimulates sirtuins in a different way. Both
ingredients can already be found in specialty vitamins. Â â€œWe expect
a synergistic effect [from] combining them,â€ he says.”
which makes it very clear that the Elysium Health product contains
both NR and pterostilbene, the same as the LEF product. Since both
of these are available from Chromadex, perhaps the Elysium Health
product does use ingredients from them. In which case Elysium Health
is counting on the scientific reputations of its owners to
competitively sell more product than other supplement suppliers such
as LEF who already have essentially the same product available.
As for taking NAD directly, this had been tried many ways for
decades and it appears that it does not survived digestion (and is
no better that taking nicotinamide) when orally ingested. Even used
sublingually its benefit is has no clear evidence (I have also taken
sublingual NADH for many, many years).
Sorry but I don’t have time to provide references, but I am sure you
can find them by searching and the LERDIT development wiki page that
I made public and to which I gave the link in another reply will
likely have some of this information on it.
The eventual home for *all* currently accessible, practically usable, scientifically evidential methods for increasing healthy longevity.
On Feb 3, 2015 12:30 PM, “Steven Charlap,
I would be
interested to get the group’s perspective on this product.http://ift.tt/1u0zpVD