There is some information on blood and plasma experiments here:http://ift.tt/1Ca8V5C
Alkast is doing a small 18 person test using transfusions on AL patients to see if there is any improvement too. SENS is also looking at Parabiosis and circulating blood factors too as are Amy Wagers, Conboy etc… My concern about the Alkast study is they have focused on AL rather than say heart disease which would be more preference as improvement in tissue/health would be easily quantifiable and less subjective compared to cognitive ability assesements to measure improvements.
There were some comparison figures for factors in young vs old blood somewhere but I have not managed to locate them again. It is clear that restoring a younger blood phenotype restores tissues in animal studies and I suspect similar would occur in the human body too. GDF-11 was certainly one factor but alone I do not think its effects will be so profound.
A proposal for a similar dialysis type intervention using blood factors was proposed recently here:
The Scrubber SENS developed a few years ago is apparently still ongoing though they have not worked out how to target Senescent T Cells only using cell surface markers, It is apparently part of SENS backed research into heterochronic plasmapheresis program at UC Berkeley according to Michael Rae from SENS.
I could see a blood scrubber that balances blood factors and removes senescent cells as being a very good step towards rejuvenation.
From: “firstname.lastname@example.org” To: steve hill ; Gerontology Research Group Sent: Saturday, 14 February 2015, 15:09Subject: RE: [GRG] Cellular Senescence: senolysis
Is there evidence that regular or acute blood donation can improve health? I bet there is, but if so, it is surprising that such studies are not more advanced by the ever-thirsty bloodmobilers. I wonder what the optimum quantity and frequency would be? If someone has a link, please post it. Donating blood might well be quicker and easier for purging some of the blood baddies, especially any that simply have no easy exit in the normal elimination system. Perhaps we will be unrolling the parchments of our blood-letting forebearers to establish starting points for the next big rejuvenation fad!