[GRG] Scientific research into meditation–The Telomere/Telomerase Connection



As you aptly point out in your summary, research has been growing demonstrating that the benefits of meditation are indeed “also physiological.” Also, the ‘mind-body connection’ is starting to be explained in physiological and biochemical terms by some very great minds, which to me is important progress.


So I would like to add to this discussion research evidence which also demonstrates a strong Telomere/Telomerase connection. I will leave it to others much more expert than I in such matters to discuss association, causation, etc., but here is a summary of the 6 study Abstracts shown below:


1. From Elizabeth Blackburn, Elissa Epel, et.al. (2011): Subjects engaged in intensive Meditation (3 month program) showed a significant increase in Telomerase Activity (measured in PBMCs) vs. control.


2. In an admittedly Pilot study by Blackburn, Epel, et.al. (2013), subjects engaged in “brief daily yogic meditation” “showed 43% improvement in telomerase activity compared with 3.7% in the relaxation group (p = 0.05).”    


3. The groundbreaking work of Drs. Epel and Blackburn in demonstrating the very powerful connection between stress and reduced telomere length (e.g., among caregivers) is well known, and here, Rita B. Effros, et. al. (2008) appear to identify at least one potential common biochemical link involved in both the Stress-Telomere Length connection and perhaps also the Meditation-Telomerase relationship: cortisol, where the authors “demonstrate that exposure of human T lymphocytes to cortisol is associated with a significant reduction in telomerase activity.” And that: “Higher concentrations of hydrocortisone, comparable to those that might be reached in vivo during stress, reduced telomerase activity by as much as 50%.” 


4. Similarly, Blackburn, Epel, et.al. (2012) demonstrate an association between higher cortisol levels and shorter telomeres.


5. and 6. Where the authors demonstrate a positive impact of meditation and/or mindfulness programs in reducing cortisol levels, which should benefit telomerase activity and telomere length.


I hope this helps the group study and understand the dynamics of meditation, and its impact, with what I believe is important additional evidence and knowledge.


David Cross 


Telomere Biosciences, LLC.

David B. Cross

Founder & President

Cell: 917.370.7456



TELO-100 with T-Activator 150

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About Johnny Adams

My full-time commitment is to slow and ultimately reverse age related functional decline to increase healthy years of life. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Carl I. Bourhenne Medical Research Foundation (Aging Intervention Foundation), an IRS approved 501(c)(3) nonprofit. http://www.AgingIntervention.org Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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