Re: [GRG] FW: Quantifying the Effectiveness of Anti-Aging Interventions

Dear Dr. Katcher: First let me introduce myself :I’m a Cornell Ph.D. trained in organic-biochemistry & physical-polymer chemistry with a 65 year career (6 academic & 36 industrial-corporate followed by 23 years consulting with the past 13 years devoted to aging research).I was introduced to the aging research field at the first commercial (2002) conference  organized by SRI (of New York) by Johnny Adams & David Palella (recently deceased).Steve Coles & I met in 2003, I joined GRG & we initiated the Supercentenarian Research Foundation early in 2004. SRF was founded formally by  group of 18 of us ( many on this GRG list) later that year , was incorporated in Pennsylvania under the Board leadership of Doros Platika (ED) , Steve Coles, Stanley Primmer & David Gobel. SRF went on to make one of the major discoveries of the last decade (TTR-Amyloidosis) on a “shoestring” i.e. with very little money.Since 2004, I have cofounded 3 other aging research organizations: 1. LDIC, the Longevity Dividend Initiative Consortium (June 2010, initiated by George Martin & me with the AGE Board’s support) whose Mission is to:a) Unite all of the major 501(c)(3) non-profit aging research organizations under a cooperative business-research -strategic-plan AND b) To get the much-needed money to finance significantly increased aging research Part a) was accomplished starting with an organizational meeting on March 7, 2011 at the EMF, Ellison Medical Foundation followed by hard work over a few years to try to influence Congress & the Administration to increase aging research funding. These efforts led to a “White Paper” by Jay Olshansky (LDIC’s Economics Team members) on the positive economic impact of increasing aging research funding. LDIC members included: GSA, AGE ,AFAR, EMF, the Alliance for Aging Research, NIA-NIH, Mayo , Glenn Foundation , the Buck Institute and the Economics Team(Jay Olshansky, Dana Goldman, Eileen Crimmin , David Cutler). Part b) is still a work in progress; no money has yet been raised.2.MARC, the Mouse Aging Research Consortium, cofounded at the June 2010 AGE meeting by 11 of us, mostly GRG List members. No money was raised, so this organization remains dormant. 3. GHF, the Geroscience  Healthspan Forum, cofounded in June 2013 by Johnny Adams & me. GHF is totally devoted to helping to fill the huge gap between decades of quality aging research and its translation into practical human clinical applications. GHF is a small, all-volunteer group with a Business-Research-Strategic plan but, no seed money.  Now, with that historical preamble, a simple question about Linus Pauling & taking megadoses of Vitamin C: 1. What are the latest best recommendations for Vitamin C supplementation?AND 2. Didn’t Pauling & his wife take 8-10 grams/day of Vitamin C yet BOTH died of cancer? If this is correct , can Vitamin C actually be pro-cancer by ROS creating new & deleterious free radicals by normal single electron abstracting mechanisms?  Elliot   


About Johnny Adams

My full-time commitment is to slow and ultimately reverse age related functional decline to increase healthy years of life. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Carl I. Bourhenne Medical Research Foundation (Aging Intervention Foundation), an IRS approved 501(c)(3) nonprofit. Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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