Oh do tell Harold? What is the alternative to human donors? Animal Plasma?
From: Dr. Harold Katcher To: Mike Darwin ; Gerontology Research Group Sent: Sunday, 8 March 2015, 2:29Subject: Re: [GRG] Plasma Factors and aging
What you say makes sense – if the work is done here. Also you can pay volunteers twice the market rate and pass the cost onto the customer – it still wouldn’t be anything near the cost of a new monoclonal antibody treatment or heart surgery – which it could replace. It requires no new technology and represent a means for money transfer from the old to the young – the young can give (even at much less frequency than plassers) to provide several people with plasma and be able to store a supply for themselves over the course of say four years. Well assuming it works – or can be made to work – what are the alternatives – well one the obvious one is to isolate all of the molecular species that constitute the age determining molecules and adjust their concentrations (including the concentrations of those ‘pro-aging’ molecules like the various pro-inflammatory factors like TNF, IL-6 etc. So it would seem, if that were needed, to require removal and replacement of plasma – assuming all the molecular species could be easily produced…. But we don’t know the species, and artificial production would be enormously more expensive than using plasma sold by disease-free youth (an impetus for them to remain so) – and provide both populations with a new life. I don’t see harm in that – but let me just say – experiments done so far reveal another potential path that would spare both people and cost (not that people are harmed in plasma exchange).