The combination of a focus on the central nervous system, especially the hypothalamus and circulating plasma factors seems a more promising approach than telomere length in myoblasts in the study of human aging. I look forward to hearing more of your thoughts on this approach.
At least one of the problems may be that the hypothalamus is hard to get to (in a living person). This should not alter your reasoning process.
On Tue, Mar 24, 2015 at 3:48 AM, steve hill wrote:
Fascinating and further evidence for intervention via Epigenetic reprogramming of the system.
Paraboisis has hinted at this with rejuvenation of cognitive function in mice, could circulating youthful blood factors possibly restore some level of youthful function to the hypothalamus and its endocrines?
Surely if the Hypothalamus is the central controller of aging/metabolism would it not make the ideal target for intervention?
From: “Steven Charlap, MD” To: Gerontology Research Group Sent: Tuesday, 24 March 2015, 3:15Subject: [GRG] Discovery can help stop emergence of age-related neurodegenerative diseases