Dear GRG Member,
We’re a step closer to reversing aging by modifying the epigenome.
Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome — or changes to the genome that do not involve changes in DNA sequence.
As we age, epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis.
Two of the most characterized epigenetic modifications are DNA methylation and histone modification.
2) The Kurzweil AI team brings us news of this advance:
- Duke University researchers have developed a new method to precisely control when genes are turned on and active: by manipulating the epigenome.
- The article discusses master control, promoters and enhancers, and people
- It uses the gene-targeting system CRISPR, now used to cut and paste DNA sequences in the human genome
- They used it to activate the gene promoters
- Abstract of Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
Thanks Kurzweil team. Full article here:
CLICK HERE for the Main Foundation Web Site: Carl I. Bourhenne Medical Research Foundation / Aging Intervention Foundation
About Johnny Adams: Johnny Adams
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Email: JAdams – at – AgingIntervention dot org