Re: [GRG] Editorial: Why Should Aging Be Considered a Weak Force?


I hope you are feeling better than last time you wrote.

The GRG-list seems to have “gone to sleep” in recent weeks. (Come on Members; participate!)

I have a couple of brief comments on a couple of your statements (below) which I hope you won’t regard as silly.


On Fri, Aug 29, 2014 at 11:44 AM, L. Stephen Coles M.D. Ph.D. wrote:

To Members and Friends of the Los Angeles Gerontology
Research Group:”Compared with Growth and
Development, Aging (Entropy) Is a Comparatively Weak Force”Summary:
1. If aging is a stochastic (time random), inevitable (inexorable),
constant (continuous), relentless process that chips away at us from day
to day,
why are no (non-progeric) children born old

Steve, I would argue that no children (babies?) are born “old” because there are rate-limiting processes at work. In other words, whilst in utero, the foetus is subject both to its own internal developmental mechanism and to influences from the mother (hormonal?) and there are certain rates beyond which it cannot age. Thus, even babies with progeria do not begin their accelerated “aging” until after they have been born. So, I am arguing that aging is NOT a stochastic, constant process UNTIL after birth and (usually) UNTIL after normal developmental processes have run their course (around age 20 or so). THEN true aging begins….


and why do we get old and die
according to a precise exponential (Gompertzian) curve as a function

of chronological age (and gender)?
Answer: Compared with the growth and development of complex multicellular
organisms starting from a single cell, net/net — intrinsic aging is
largely an
informationally-disorganizing process of very fine granularity (operating
the molecular level — from nanometers to microns) secondary to thermal
Brownian) Motion (entropy), and it’s not on the radar compared with
growth, even though it’s present well before birth.  

Which suggests that, given the application of energy in the right places, at the right times, it might be reversible.

2.  Aging is weak in the same sense as gravity is weak compared with
electomagnetism in cosmology; yet it’s gravity that shapes the observable
(i.e., the gross distribution of trillions of stars in an elaborate web
of trillions of galaxies). 


About Johnny Adams

My full-time commitment is to slow and ultimately reverse age related functional decline to increase healthy years of life. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Carl I. Bourhenne Medical Research Foundation (Aging Intervention Foundation), an IRS approved 501(c)(3) nonprofit. Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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