Re: [GRG] What successes have there been in the creation of aging therapies?

On 05/31/2014 03:02 PM, John M. “Johnny” Adams wrote:
> One of my expert fundraising consultants asked “What successes have there
> been in the creation of aging therapies?”
> Donors will ask this question. We need compelling answers. (However – if
> were already 100% successful we’d be young again and off doing something
> else!)
I’d say that this is chasing the wrong donor demographic. Most potential
donors are just as much sheep as the rest of the world and will only
invest in what they see as a sure thing – i.e. something that is already
successful. See Peter Theil’s remarks on the need for venture
philanthropy and fundraising built on a willingness to take risks. See
also the behavior of donors with regard to stem cell research and
development. If you interact with donors who will only assist existing
success, which is most of them, I’d say the best thing you can do with
respect to aging is point them to cancer and stem cell research (as both
of those fields by their very nature are required to solve important
problems in aging in order to move ahead) and otherwise write them off.

What is needed are donors who can join the dots a little more: someone
to whom you can present the present state of evidence for, say,
senescent cell attrition and say “this needs to get to the clinic
post-haste” and get them to a place at which they are comfortable being
the bridge between compelling evidence and clinical trials. Glucosepane
breakdown is another area in which strides could be made based on
compelling evidence. But in neither of these cases, or other examples
relevant to aging I might bring up, is there anything that could be
called success in building a therapy. The whole problem is that there
are no therapies! We stand at that awkward stage of bootstrapping
wherein everything will go so very much faster with a success in the
bag, but few of the sheep are going to invest until that happens.


About Johnny Adams

My full-time commitment is to slow and ultimately reverse biological aging and age related decline for more years of healthy living. I’ve been active in this area since the 1970s, steadily building skills and accomplishments. I have a good basic understanding of the science of aging, and have many skills that complement those of scientists so they can focus on science to advance our shared mission. Broad experience Top skills: administration, management, information technology (data and programming), communications, writing, marketing, market research and analysis, public speaking, forging ethical win-win outcomes among stakeholders (i.e. high level "selling"). Knowledge in grant writing, fundraising, finance. Like most skilled professionals, I’m best described as a guy who defines an end point, then figures out how to get there. I enjoy the conception, design, execution and successful completion of a grand plan. Executive Director Gerontology Research Group (GRG). Manages Email discussion forum, web site, meetings and oversees supercentenarian (oldest humans, 110+ years) research. CEO / Executive Director Aging Intervention Foundation (dba for Carl I. Bourhenne Medical Research Foundation), an IRS approved 501(c)(3) nonprofit. Early contributor to Supercentenarian Research Foundation. Co-Founder Geroscience Healthspan Forum. Active contributor to numerous initiatives to increase healthy years of life. Co-authored book on conventional, practical methods available today to slow the processes of aging – nutrition, exercise, behavior modification and motivation, stress reduction, proper supplementation, damage caused by improper programs, risk reduction and others. Fundamental understanding of, and experience in the genomics of longevity (internship analyzing and curating longevity gene papers). Biological and technical includes information technology, software development and computer programming, bioinformatics and protein informatics, online education, training programs, regulatory, clinical trials software, medical devices (CAT scanners and related), hospital electrical equipment testing program. Interpersonal skills – good communication, honest, well liked, works well in teams or alone. Real world experience collaborating in interdisciplinary teams in fast paced organizations. Uses technology to advance our shared mission. Education: MBA 1985 University of Southern California -- Deans List, Albert Quon Community Service Award (for volunteering with the American Longevity Association and helping an elderly lady every other week), George S. May Scholarship, CA State Fellowship. BA psychology, psychobiology emphasis 1983 California State University Fullerton Physiological courses as well as core courses (developmental, abnormal etc). UCLA Psychobiology 1978, one brief but fast moving and fulfilling quarter. Main interest was the electrochemical basis of consciousness. Also seminars at the NeuroPsychiatric Institute. Other: Ongoing conferences, meetings and continuing education. Aging, computer software and information technology. Some molecular biology, biotech, bio and protein informatics, computer aided drug design, clinical medical devices, electronics, HIPAA, fundraising through the Assoc. of Fundraising Professionals. Previous careers include: Marketing Increasing skill set and successes in virtually all phases, with valuable experience in locating people and companies with the greatest need and interest in a product or service, and sitting across the table with decision makers and working out agreements favorable to all. Information Technology: Management, data analysis and programming in commercial and clinical trials systems, and bioinformatics and protein informatics. As IT Director at Newport Beach, CA based technology organization Success Family of Continuing Education Companies, provided online software solutions for insurance and financial professionals in small to Fortune 500 size companies. We were successful with lean team organization (the slower moving competition was unable to create similar software systems). Medical devices: At Omnimedical in Paramount CA developed and managed quality assurance dept. and training depts. for engineers, physicians and technicians. Designed hospital equipment testing program for hospital services division. In my early 20’s I was a musician, and studied psychology and music. Interned with the intention of becoming a music therapist. These experiences helped develop valuable skills used today to advance our shared mission of creating aging solutions.
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